Nanobiomaterials in drug delivery :
Nanobiomaterials in drug delivery : applications of nanobiomaterials /
edited by Alexandru Mihai Grumezescu.
- 1 online resource
Includes bibliographical references and index.
Front Cover; Nanobiomaterials in Drug Delivery; Copyright Page; Contents; List of contributors; Preface of the series; Preface; About the Series (Volumes I-XI); About Volume IX; 1 Nanobiomaterials in drug delivery; Abbreviations; 1.1 Introduction; 1.1.1 Parameters of Delivery of Nanoparticles into Biological Systems; 1.1.2 Intratumor Drug Release; 1.1.3 Biological Clearance; 1.1.4 Toxicity of Nanoparticles; 1.2 Preparation and Characterization of Nanomaterials; 1.2.1 Preparation; 1.2.2 Characterization; 1.2.2.1 Physicochemical characterization. 1.3 Nanotechnology-Assisted Formulating of Poorly Water-Soluble Compounds1.4 Biodegradable Polymers Used in Controlled Drug Delivery; 1.5 Multifunctional Nanomaterials for Cancer Therapy; 1.5.1 Targeting; 1.5.2 Imaging; 1.5.3 Chemotherapy; 1.6 Chemical Conjugation of Nanomaterials; 1.6.1 pH-Sensitive Linkages Used for Bioconjugation of Nanomaterials; 1.6.2 Other Chemical Linkages Used for Bioconjugation of Nanomaterials; 1.7 Conclusions; Acknowledgments; References; 2 Dendrimers in drug delivery; 2.1 Introduction; 2.2 Mechanisms of Interaction Between Dendrimers and Drug Molecules. 2.3 Dendrimers as Carriers of Various Types of Drugs2.3.1 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); 2.3.2 Anticancer Drugs; 2.3.3 Other Drugs; 2.4 Routes of Administration of Drug-Dendrimers Complexes; 2.4.1 Dendrimers in Intravenous Drug Delivery; 2.4.2 Dendrimers in Oral Drug Delivery; 2.4.3 Dendrimers in Transdermal Drug Delivery; 2.4.4 Dendrimers in Ocular Drug Delivery; 2.4.5 Dendrimers in Pulmonary Drug Delivery; 2.5 Conclusions and Further Prognosis; Acknowledgments; References; 3 Lipid nanoparticles as non-viral vectors for siRNA delivery: concepts and applications. 3.1 Introduction3.2 siRNA: Definition, Mechanism, and Applications; 3.3 Hurdles for siRNA Delivery; 3.4 Strategies to Overcome the Hurdles of siRNA Delivery; 3.4.1 Chemical Modifications in siRNA; 3.4.2 Physical Methods for siRNA Delivery; 3.4.3 Viral Carriers for siRNA Delivery; 3.4.4 Non-viral Carriers for siRNA Delivery; 3.5 Liposomes: The Influence of Charge and Lipid Composition for siRNA Delivery; 3.5.1 Cationic Lipid-Based siRNA Delivery Systems; 3.5.2 Neutral Lipid-Based siRNA Delivery Systems; 3.5.3 Anionic Lipid-Based siRNA Delivery Systems; 3.5.4 Stealth Liposomes. 3.6 Targeted Delivery of siRNA-Loaded Liposomes3.7 Combined Therapy of siRNA-Loaded Liposomes and Conventional Small-Molecule Drugs; 3.8 siRNA-Loaded Liposomes Associated with Physical Methods; 3.9 siRNA-Loaded Liposomes: Clinical Studies; 3.10 Conclusions and Perspectives; References; 4 Nanobiomaterials: Novel nanoplatforms for protein and peptide delivery; 4.1 Introduction; 4.2 Proteins/Peptides as Therapeutics; 4.2.1 Group I-Protein Therapeutics with Enzymatic or Regulatory Activity; 4.2.2 Group II-Protein Therapeutics with Special Targeting Activity; 4.2.3 Group III-Proteinaceous Vaccines.
9780323428668 0323428665 9780323428897 0323428894
Nanostructured materials.
Nanomedicine.
Nanobiotechnology.
TECHNOLOGY & ENGINEERING / Engineering (General)
TECHNOLOGY & ENGINEERING / Reference
Nanobiotechnology.
Nanomedicine.
Nanostructured materials.
Electronic books.
TA418.9.N35
620.1/15
Includes bibliographical references and index.
Front Cover; Nanobiomaterials in Drug Delivery; Copyright Page; Contents; List of contributors; Preface of the series; Preface; About the Series (Volumes I-XI); About Volume IX; 1 Nanobiomaterials in drug delivery; Abbreviations; 1.1 Introduction; 1.1.1 Parameters of Delivery of Nanoparticles into Biological Systems; 1.1.2 Intratumor Drug Release; 1.1.3 Biological Clearance; 1.1.4 Toxicity of Nanoparticles; 1.2 Preparation and Characterization of Nanomaterials; 1.2.1 Preparation; 1.2.2 Characterization; 1.2.2.1 Physicochemical characterization. 1.3 Nanotechnology-Assisted Formulating of Poorly Water-Soluble Compounds1.4 Biodegradable Polymers Used in Controlled Drug Delivery; 1.5 Multifunctional Nanomaterials for Cancer Therapy; 1.5.1 Targeting; 1.5.2 Imaging; 1.5.3 Chemotherapy; 1.6 Chemical Conjugation of Nanomaterials; 1.6.1 pH-Sensitive Linkages Used for Bioconjugation of Nanomaterials; 1.6.2 Other Chemical Linkages Used for Bioconjugation of Nanomaterials; 1.7 Conclusions; Acknowledgments; References; 2 Dendrimers in drug delivery; 2.1 Introduction; 2.2 Mechanisms of Interaction Between Dendrimers and Drug Molecules. 2.3 Dendrimers as Carriers of Various Types of Drugs2.3.1 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); 2.3.2 Anticancer Drugs; 2.3.3 Other Drugs; 2.4 Routes of Administration of Drug-Dendrimers Complexes; 2.4.1 Dendrimers in Intravenous Drug Delivery; 2.4.2 Dendrimers in Oral Drug Delivery; 2.4.3 Dendrimers in Transdermal Drug Delivery; 2.4.4 Dendrimers in Ocular Drug Delivery; 2.4.5 Dendrimers in Pulmonary Drug Delivery; 2.5 Conclusions and Further Prognosis; Acknowledgments; References; 3 Lipid nanoparticles as non-viral vectors for siRNA delivery: concepts and applications. 3.1 Introduction3.2 siRNA: Definition, Mechanism, and Applications; 3.3 Hurdles for siRNA Delivery; 3.4 Strategies to Overcome the Hurdles of siRNA Delivery; 3.4.1 Chemical Modifications in siRNA; 3.4.2 Physical Methods for siRNA Delivery; 3.4.3 Viral Carriers for siRNA Delivery; 3.4.4 Non-viral Carriers for siRNA Delivery; 3.5 Liposomes: The Influence of Charge and Lipid Composition for siRNA Delivery; 3.5.1 Cationic Lipid-Based siRNA Delivery Systems; 3.5.2 Neutral Lipid-Based siRNA Delivery Systems; 3.5.3 Anionic Lipid-Based siRNA Delivery Systems; 3.5.4 Stealth Liposomes. 3.6 Targeted Delivery of siRNA-Loaded Liposomes3.7 Combined Therapy of siRNA-Loaded Liposomes and Conventional Small-Molecule Drugs; 3.8 siRNA-Loaded Liposomes Associated with Physical Methods; 3.9 siRNA-Loaded Liposomes: Clinical Studies; 3.10 Conclusions and Perspectives; References; 4 Nanobiomaterials: Novel nanoplatforms for protein and peptide delivery; 4.1 Introduction; 4.2 Proteins/Peptides as Therapeutics; 4.2.1 Group I-Protein Therapeutics with Enzymatic or Regulatory Activity; 4.2.2 Group II-Protein Therapeutics with Special Targeting Activity; 4.2.3 Group III-Proteinaceous Vaccines.
9780323428668 0323428665 9780323428897 0323428894
Nanostructured materials.
Nanomedicine.
Nanobiotechnology.
TECHNOLOGY & ENGINEERING / Engineering (General)
TECHNOLOGY & ENGINEERING / Reference
Nanobiotechnology.
Nanomedicine.
Nanostructured materials.
Electronic books.
TA418.9.N35
620.1/15