Studies in natural products chemistry. Volume 49 / edited by Atta-ur-Rahman.

Includes index.

Online resource; title from PDF title page (ScienceDirect, viewed September 19, 2016).

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XIII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

Front Cover; Studies in Natural Products Chemistry; Studies in Natural Products Chemistry; Copyright; Contents; Contributors ; Preface; 1 -- Echinoderms: A Review of Bioactive Compounds With Potential Health Effects ; INTRODUCTION; BIOLOGICAL ACTIVITIES WITH POTENTIAL BENEFIT FOR HEALTH; Antibacterial and Antifungal Activities; Anti-inflammatory Activity; Anticancer Activity; Antioxidant Activity; Immunomodulatory Activity; NATURAL PRODUCTS DERIVED FROM ECHINODERMS MOLECULES WHICH/ AVE POTENTIAL HEALTH EFFECTS; Saponins; Peptides; Sphingolipids and Fatty Acids; Pigments.

Other Bioactive ExtractsCONCLUSION; DECLARATION OF INTEREST; REFERENCES; 2 -- Sea Cucumber Triterpene Glycosides as Anticancer Agents ; INTRODUCTION; CYTOTOXIC ACTIVITY; The Cytotoxic Activity of/ riterpene Glycosides Isolated From the Sea Cucumbers of the Order Aspidochirotida; The Cytotoxic Activity of/ riterpene Glycosides Isolated From the Sea Cucumbers of the Order Apodida; The Cytotoxic Activity of/ riterpene Glycosides Isolated From the Sea Cucumbers of the Order Dendrochirotida; Cytotoxic Activity of Triterpene Glycosides Isolated From the Sea Cucumbers of the Order Elasipodida.

ANTICANCER ACTIVITYCell Cycle Arrest; Induction of Apoptosis; Migration/Invasion/Metastasis; Angiogenesis; Multidrug Resistance; Receptors/Intracellular Targets/Pathways; Tumor Growth Suppress/ n Vivo; CONCLUSIONS; ABBREVIATIONS; ACKNOWLEDGMENTS; REFERENCES; 3 -- Cytotoxic Alkaloid Constituents of the Amaryllidaceae ; INTRODUCTION; Cytotoxic Lycorine Alkaloids; Structure-Activity Relationships Among Lycorine Alkaloids; Mechanism of Action of/ ycorine Alkaloids; Cytotoxic Crinane Alkaloids; Structure-Activity Relationships Among Crinane Alkaloids; Mechanism of Action of/ rinane Alkaloids.

Cytotoxic Phenanthridone AlkaloidsStructure-Activity Relationships Among Phenanthridone/ lkaloids; Mechanism of Action of Phenanthridone Alkaloids; Concluding Remarks; ABBREVIATIONS; ACKNOWLEDGMENTS; REFERENCES; 4 -- Bioactivity and Synthesis of Diarylheptanoids From Alpinia officinarum ; INTRODUCTION; STRUCTURES AND ISOLATION OF DIARYLHEPTANOIDS; SYNTHESIS OF DIARYLHEPTANOIDS; ANTINEUROBLASTOMA ACTIVITY OF DIARYLHEPTANOIDS; ANTITUMOR-PROMOTING AND ANTIINFLAMMATORY ACTIVITIES OF DIARYLHEPTANOIDS; ANTIVIRAL ACTIVITIES OF DIARYLHEPTANOIDS; Antiinfluenza Virus Activity.

Antirespiratory Syncytial Virus ActivityAntiviral Activity Against Other Viruses; OTHER ACTIVITIES OF/ IARYLHEPTANOIDS; MOLECULAR PHARMACOLOGICAL/ VALUATION BY TRANSLATION/ ROFILING; CONCLUSION; ABBREVIATIONS; REFERENCES; 5 -- Bioactive Secondary Metabolites From Endophytic Fungi: A Review of Biotechnological Production and Their Potential Applications ; INTRODUCTION; ENDOPHYTES AND THEIR DIVERSITY; ENDOPHYTE-HOST ASSOCIATION; ENDOPHYTES FOR BIOACTIVE/ ETABOLITE PRODUCTION; Selection of Plant for Novel Endophytes.