Nanotechnology in cancer / edited by Anshu B. Mathur.

Includes bibliographical references and index.

Front Cover; Nanotechnology in Cancer; Copyright Page; Contents; Contributors; About the Authors; Foreword; Preface; Introduction to Bio-Nanotechnology; 1 Gold nanoparticles for noninvasive radiofrequency cancer hyperthermia; Introduction; Brief Overview of Clinically Available Hyperthermia Systems; Nanoparticle-Mediated Cancer Hyperthermia; RF Interactions With AuNPs; Theoretical Frameworks for RF-Induced AuNP Heating; Joule Model; Classical and Quantum Electromagnetic Theory; Electrophoretic Model; Biological RF Activity of AuNPs In Vitro/In Vivo; Conclusion; References.

2 Silk fibroin nanoparticles and cancer therapyIntroduction; Materials and Methods; Materials; Cell Culture; Preparation of SF Solution and Curcumin Solution; Preparation of SF Nanoparticles and Curcumin-Loaded SF Nanoparticles; Characterization of Curcumin-Loaded SF Nanoparticles; Scanning electron microscopy; Atomic force microscopy; Dynamic light scattering; Drug loading efficiency; Curcumin release profile from SF nanoparticles; Biological Evaluation of Curcumin-Loaded SF Nanoparticles; Curcumin efficacy against GILM2 metastatic breast cancer cells.

Protein expression analysis using protein arrayStatistics; Results; Characterization of Curcumin-Loaded SF Nanoparticles; Morphology of curcumin-loaded SF nanoparticles; Particle size distribution of curcumin-loaded SF nanoparticles; Drug loading efficiency and release kinetics of curcumin from SF nanoparticles; Biological Evaluation of Curcumin-Loaded SF Nanoparticles; Curcumin efficacy against GILM2 metastatic breast cancer cells; Protein array analysis of apoptotic pathways activated by curcumin; Discussion; Conclusions; Acknowledgments; References; 3 Animal models in cancer nanotechnology.

Nanoparticles' Use in PharmacokineticsNanoparticles as Diagnostic Imaging Tools; Nanoparticles as a Theranostic Tool; Nanoparticles as a Treatment Tool; Conclusions; References; 4 Surgical implications of surface texturing in breast implants; Introduction; Capsular Contraction; The Cellular Response to Implant Surface Texturing; The Textured Implant: History and Development; The Silicone Shell; Salt Loss Technique; Stamping Technique; Surface Texturing and Cellular Ingrowth; Utility of Nanotechnology; Three-Dimensional Surface Printing; Surface Nanoparticles and Infection Prevention.

ConclusionReferences; 5 Nanoscale engineering of silk fibroin scaffold architecture to repair patient-specific cancer defects; Introduction; Materials and Methods; Scaffold Preparation; SF Solution Particle Size Measurement Using DLS; 3D Architecture Characterization Using SEM; Porosity Measurement; Mechanical Properties Measurement Using Uniaxial Tensile Testing; Conformation Analysis Using FTIR; Statistical Analysis; Results; Effect of SF Concentration on SF Particle Size in Solution; Effect of SF Concentration on SF Scaffold Properties; Effect of the Filter Size on SF Scaffold Properties.

Print version record.

This book covers current nanotechnology-based nanotherapeutics involving gold nanoparticles, colloids, gels, magnetic nanoparticles, radiofrequency, gene therapy, biological particles, and the intermolecular interactions associated with nanoparticle based cancer therapy in vivo. Both scientific and clinical aspects are considered to make the connection between cancer and effective drug delivery and therapeutic strategies.