TY  - BOOK
AU  - Pucheu,Sylvie
AU  - Radziwon,Kelly E.
AU  - Salvi,Richard
ED  - SpringerLink (Online service)
TI  - New Therapies to Prevent or Cure Auditory Disorders
SN  - 9783030404130
AV  - RC321-580 
U1  - 612.8 23
PY  - 2020///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Neurosciences
KW  - Otorhinolaryngology
N2  - This volume focuses on new molecular therapies that aim to prevent specific pathologies of the ear, like age-related hearing loss, noise-induced hearing loss and ototoxicity. The book discusses the regenerative capacity of hair cells in the inner ear, exploring the idea that hair cells' capacity to regenerate appears "repressed" in adult mammals, but that it will be possible to re-activate regeneration with an appropriate therapeutic approach. The book provides an overview of inflammatory and immune cells in the cochlear lateral wall, the pathways involved in cochlear damage, and their potential as therapeutic targets. It also describes the significant advances in animal models which play an important role in revealing the underlying mechanisms and treatment for tinnitus and hyperacusis. Finally, the book describes two new automatic and robust measures to evaluate hearing loss and tinnitus in preclinical models
UR  - https://doi.org/10.1007/978-3-030-40413-0
ER  -