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020 _a9781420003147 (ebook : PDF)
040 _aFlBoTFG
_cFlBoTFG
090 _aRC720
_b.P373 2007
092 _a616.200471
_bP273
245 0 0 _aParticle toxicology
_h[electronic resource] /
_cedited by Ken Donaldson, Paul Borm.
260 _aBoca Raton :
_bCRC Press/Taylor & Francis Group,
_cc2007.
300 _a434 p., [8] p. of plates :
_bill. (some col.).
504 _aIncludes bibliographical references and index.
505 0 _aAn introduction to particle toxicology: from coal mining to nanotechnology / Paul J.A. Borm and Ken Donaldson -- Mineralogy and structure of pathogenic particles / Tim Jones and Kelly B�ruB� -- Particle dosimetry: deposition and clearance from the respiratory tract and translocation towards extra-pulmonary sites / Wolfgang G. Kreyling ... [et al.] -- Particulate air pollutants and small airway remodeling / Andrew Churg -- Particle-mediated extracellular oxidative stress in the lung / Frank J. Kelly and Ian S. Mudway -- Particles and cellular oxidative and nitrosative stress / Dale W. Porter, Stephen S. Leonard, and Vincent Castranova -- Interaction of particles with membranes / Barbara Rothen-Rutishauser, Samuel Sch�rch, and Peter Gehr -- Particle-associated metals and oxidative stress in signaling / James M. Samet and Andrew J. Ghio -- Proinflammatory effects of particles on macrophages and epithelial cells / Vicki Stone ... [et al.] -- Cell-signaling pathways elicited by particulates / Jamie E. Levis and Brooke T. Mossman -- Particle-associated organics and proinflammatory signaling / Francelyne Marano, Sonja Boland, and Armelle Baeza-Squiban -- The asbestos model of interstitial pulmonary fibrosis: TNF-a and TGF-b1 as mediators of asbestos-induced lung fibrogenesis / Deborah E. Sullivan and Arnold R. Brody --
505 0 _aEffect of particles on the immune system / M. Ian Gilmour, Tina Stevens, and Rajiv K. Saxena -- Effects of particles on the cardiovascular system / Nicholas L. Mills ... [et al.] -- Susceptibility to particle effects / Steven R. Kleeberger and Reuben Howden -- Genotoxic effects of particles / Roel P.F. Schins and Tom K. Hei -- Approaches to the toxicological testing of particles / Ken Donaldson ... [et al.] -- Models for testing the pulmonary toxicity of particles: Lung bioassay screening studies in male rats with a new formulation of TiO2 particulates / David B. Warheit, Kenneth L. Reed, and Christie M. Sayes -- Air pollution and human brain pathology: a role for air pollutants in the pathogenesis of Alzheimer's disease / Lilian Calder�n-Garcidue�as and William Reed -- Biologically based lung dosimetry and exposure-dose-response models for poorly soluble inhaled particles / Lang Tran and Eileen Kuempel -- Nanoparticles in medicine / Paul J.A. Borm and Detlef Muller-Sch�lte -- The toxicology of inhaled particles: summing up an emerging conceptual framework / Ken Donaldson, Lang Tran, and Paul J.A. Borm.
530 _aAlso available in print edition.
_bCRC Press (http://www.crcpress.com)
538 _aMode of access: World Wide Web.
650 0 _aPulmonary toxicology.
650 0 _aParticles
_xToxicology.
655 7 _aElectronic books.
_2lcsh
700 1 _aDonaldson, Kenneth,
_cDSc.
700 1 _aBorm, Paul.
776 1 _z9780849350924
856 4 0 _uhttp://marc.crcnetbase.com/isbn/9781420003147
_qapplication/PDF
_zDistributed by publisher. Purchase or institutional license may be required for access.
999 _c331393
_d331329