000			06665cam a2200625Ia 4500
001			ocn944309993
003			OCoLC
005			20190719103219.0
006			m o d
007			cr un|||||||||
008			160311s2016 enk ob 001 0 eng d
040			_aIDEBK _beng _epn _cIDEBK _dN$T _dYDXCP _dN$T _dOPELS _dN$T _dUIU _dOCLCF _dCDX _dEBLCP _dOCLCQ _dOCLCO _dOCLCQ _dU3W _dMERUC _dD6H _dAU@ _dOCLCO _dMERER _dOCLCO _dOCLCQ _dWYU _dOCLCA _dOCLCQ _dOCLCA _dOCLCQ
016	7		_a101684853 _2DNLM
019			_a945612621 _a953859405 _a1066648716
020			_a0323428878 _q(electronic bk.)
020			_a9780323428873 _q(electronic bk.)
020			_z9780323428644
020			_z0323428649
035			_a(OCoLC)944309993 _z(OCoLC)945612621 _z(OCoLC)953859405 _z(OCoLC)1066648716
050		4	_aRM267
060	0	0	_a2016 F-773
060	1	0	_aQV 250
072		7	_aMED _x071000 _2bisacsh
082	0	4	_a615.7922 _223
245	0	0	_aNanobiomaterials in antimicrobial therapy : _bapplications of nanobiomaterials / _cedited by Alexandru Mihai Grumezescu.
260			_aKidlington, Oxford, UK : _bWilliam Andrew is an imprint of Elsevier, _c2016.
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aApplications of nanobiomaterials ; _vvolume 6
504			_aIncludes bibliographical references and index.
588	0		_aPrint version record.
520			_aNanobiomaterials in Antimicrobial Therapy presents novel antimicrobial approaches that enable nanotechnology to be used effectively in the treatment of infections. This field has gained a large amount of interest over the last decade, in response to the high resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The books covers various aspects: mechanisms of toxicity for inorganic nanoparticles against bacteria; the development of excellent carriers for the transport of a high variety of antimicrobials; the use of nanomaterials to facilitate both diagnosis and therapeutic approaches against infectious agents; strategies to control biofilms based on enzymes, biosurfactants, or magnetotactic bacteria; bacterial adhesion onto polymeric surfaces and novel materials; and antimicrobial photodynamic inactivation. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians.
505	0		_aFront Cover; Nanobiomaterials in Antimicrobial Therapy; Copyright Page; Contents; List of contributors; Preface of the series; Preface; About the Series (Volumes I-XI); About Volume VI; 1 Antimicrobial photoinactivation with functionalized fullerenes; 1.1 Introduction; 1.2 Photosensitizers; 1.3 Photochemistry of PDT; 1.4 Fullerenes Acting as Photosensitizers; 1.5 Biocompatibility of Fullerenes; 1.6 Chemical Design of Fullerene Derivatives; 1.6.1 Examples of the Synthesis of Mono- and Polycationic Fullerene Derivatives; 1.6.2 Synthesis of Hexa-Anionic Fullerene Derivatives.
505	8		_a1.6.3 Synthesis of Chromophore-Linked Fullerene Derivatives1.7 Photochemical and Photophysical Properties of Fullerenyl Molecular Micelles and Chromophore-Fullerene Conjugates; 1.8 Fullerenes for Antimicrobial Inactivation; 1.9 Conclusions; Acknowledgments; References; 2 Toxicity of inorganic nanoparticles against prokaryotic cells; 2.1 Introduction; 2.2 Inorganic Nanoarchitectonics with Anti-Infective Potential; 2.2.1 Unmodified Nanomaterials with Natural Antimicrobial Activity; 2.2.1.1 Silver nanoparticles; 2.2.1.1.1 Cytotoxicity; 2.2.1.1.2 Clinical studies; 2.2.1.2 Selenium nanoparticles.
505	8		_a2.2.1.2.1 Toxicity2.2.1.3 Copper nanoparticles; 2.2.1.3.1 Cytotoxicity; 2.2.1.4 Titanium dioxide nanoparticles; 2.2.1.4.1 Cytotoxicity; 2.2.1.5 ZnO nanoparticles; 2.2.2 Modified Nanomaterials with Antimicrobial Activity; 2.2.2.1 Phytochemical-Modified Nanomaterials; 2.2.2.2 Peptide- modified nanomaterials; 2.2.2.3 Nanomaterials Modified with Commercial Antibiotics; 2.3 Conclusions and Perspectives; References; 3 Antimicrobial magnetosomes for topical antimicrobial therapy; 3.1 Introduction; 3.1.1 Biosynthesis of Magnetic Particles; 3.1.1.1 Biologically induced mineralization.
505	8		_a3.1.1.2 Biologically controlled biomineralization3.1.1.2.1 Magnetite in eukaryotic microbes; 3.1.1.3 Magnetotactic bacteria; 3.1.1.4 Characteristics and attributes of magnetosomes; 3.1.1.4.1 Attributes of magnetosomes; 3.1.1.5 Steps involved in magnetosome formation; 3.1.1.6 Functionalization of magnetosomes; 3.1.1.7 Biochemical characteristics of magnetosome membrane; 3.1.1.8 Extraction and purification of magnetosomes for antimicrobial activity; 3.1.1.9 Surface modification of magnetosomes; 3.1.1.10 Applications of magnetosomes; 3.1.2 Green Synthesis of Magnetic Nanoparticles.
505	8		_a3.1.2.1 Extracellular synthesis of iron oxide particles3.2 Biofilm Formation; 3.2.1 Characteristics of Biofilm in Medical Devices; 3.2.2 Bacterial Biofilm in Diseases; 3.2.3 Structure of Bacterial Biofilm; 3.2.3.1 Genomics and proteomics of biofilm formation in Gram-negative bacteria; 3.2.3.2 Structure of Gram-negative cell wall; 3.2.4 Candida albicans and Biofilm; 3.2.4.1 Mechanism of drug resistance; 3.2.5 Failure of Antibiotics to Penetrate Biofilm; 3.3 Nanobiomaterials Against Biofilm Formation; 3.3.1 Mechanism of Toxicity of Nanoparticles; 3.3.1.1 Intracellular toxicity.
650		0	_aAnti-infective agents.
650		0	_aNanostructured materials.
650		0	_aBiomedical materials.
650		7	_aMEDICAL _xPharmacology. _2bisacsh
650		7	_aAnti-infective agents. _2fast _0(OCoLC)fst00810345
650		7	_aBiomedical materials. _2fast _0(OCoLC)fst00832586
650		7	_aNanostructured materials. _2fast _0(OCoLC)fst01032630
650	1	2	_aAnti-Infective Agents.
650	2	2	_aNanostructures _xtherapeutic use.
655		4	_aElectronic books.
655		0	_aElectronic book.
700	1		_aGrumezescu, Alexandru Mihai.
776	0	8	_iPrint version: _aGrumezescu, Alexandru. _tNanobiomaterials in Antimicrobial Therapy : Applications of Nanobiomaterials. _d: Elsevier Science, �2016 _z9780323428644
830		0	_aApplications of nanobiomaterials ; _vvolume 6.
856	4	0	_3ScienceDirect _uhttp://www.sciencedirect.com/science/book/9780323428644
999			_c503857 _d503792