000 04915cam a2200541Ii 4500
001 ocn948296971
003 OCoLC
005 20190719103232.0
006 m o d
007 cr cnu|||unuuu
008 160429s2016 enk ob 001 0 eng d
040 _aN$T
_beng
_erda
_epn
_cN$T
_dOPELS
_dN$T
_dYDXCP
_dOCLCF
_dYDX
_dUPM
_dU3W
_dD6H
_dAU@
_dWYU
019 _a958084149
_a958392409
_a1066462332
020 _a9780323428668
_qelectronic bk.
020 _a0323428665
_qelectronic bk.
020 _z9780323428668
_qprint
020 _a9780323428897
020 _a0323428894
035 _a(OCoLC)948296971
_z(OCoLC)958084149
_z(OCoLC)958392409
_z(OCoLC)1066462332
050 4 _aTA418.9.N35
072 7 _aTEC
_x009000
_2bisacsh
072 7 _aTEC
_x035000
_2bisacsh
082 0 4 _a620.1/15
_223
245 0 0 _aNanobiomaterials in drug delivery :
_bapplications of nanobiomaterials /
_cedited by Alexandru Mihai Grumezescu.
264 1 _aKidlington, Oxford, UK :
_bWilliam Andrew is an imprint of Elsevier,
_c2016.
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references and index.
588 0 _aOnline resource; title from PDF title page (ScienceDirect, viewed May 9, 2016).
505 0 _aFront Cover; Nanobiomaterials in Drug Delivery; Copyright Page; Contents; List of contributors; Preface of the series; Preface; About the Series (Volumes I-XI); About Volume IX; 1 Nanobiomaterials in drug delivery; Abbreviations; 1.1 Introduction; 1.1.1 Parameters of Delivery of Nanoparticles into Biological Systems; 1.1.2 Intratumor Drug Release; 1.1.3 Biological Clearance; 1.1.4 Toxicity of Nanoparticles; 1.2 Preparation and Characterization of Nanomaterials; 1.2.1 Preparation; 1.2.2 Characterization; 1.2.2.1 Physicochemical characterization.
505 8 _a1.3 Nanotechnology-Assisted Formulating of Poorly Water-Soluble Compounds1.4 Biodegradable Polymers Used in Controlled Drug Delivery; 1.5 Multifunctional Nanomaterials for Cancer Therapy; 1.5.1 Targeting; 1.5.2 Imaging; 1.5.3 Chemotherapy; 1.6 Chemical Conjugation of Nanomaterials; 1.6.1 pH-Sensitive Linkages Used for Bioconjugation of Nanomaterials; 1.6.2 Other Chemical Linkages Used for Bioconjugation of Nanomaterials; 1.7 Conclusions; Acknowledgments; References; 2 Dendrimers in drug delivery; 2.1 Introduction; 2.2 Mechanisms of Interaction Between Dendrimers and Drug Molecules.
505 8 _a2.3 Dendrimers as Carriers of Various Types of Drugs2.3.1 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); 2.3.2 Anticancer Drugs; 2.3.3 Other Drugs; 2.4 Routes of Administration of Drug-Dendrimers Complexes; 2.4.1 Dendrimers in Intravenous Drug Delivery; 2.4.2 Dendrimers in Oral Drug Delivery; 2.4.3 Dendrimers in Transdermal Drug Delivery; 2.4.4 Dendrimers in Ocular Drug Delivery; 2.4.5 Dendrimers in Pulmonary Drug Delivery; 2.5 Conclusions and Further Prognosis; Acknowledgments; References; 3 Lipid nanoparticles as non-viral vectors for siRNA delivery: concepts and applications.
505 8 _a3.1 Introduction3.2 siRNA: Definition, Mechanism, and Applications; 3.3 Hurdles for siRNA Delivery; 3.4 Strategies to Overcome the Hurdles of siRNA Delivery; 3.4.1 Chemical Modifications in siRNA; 3.4.2 Physical Methods for siRNA Delivery; 3.4.3 Viral Carriers for siRNA Delivery; 3.4.4 Non-viral Carriers for siRNA Delivery; 3.5 Liposomes: The Influence of Charge and Lipid Composition for siRNA Delivery; 3.5.1 Cationic Lipid-Based siRNA Delivery Systems; 3.5.2 Neutral Lipid-Based siRNA Delivery Systems; 3.5.3 Anionic Lipid-Based siRNA Delivery Systems; 3.5.4 Stealth Liposomes.
505 8 _a3.6 Targeted Delivery of siRNA-Loaded Liposomes3.7 Combined Therapy of siRNA-Loaded Liposomes and Conventional Small-Molecule Drugs; 3.8 siRNA-Loaded Liposomes Associated with Physical Methods; 3.9 siRNA-Loaded Liposomes: Clinical Studies; 3.10 Conclusions and Perspectives; References; 4 Nanobiomaterials: Novel nanoplatforms for protein and peptide delivery; 4.1 Introduction; 4.2 Proteins/Peptides as Therapeutics; 4.2.1 Group I-Protein Therapeutics with Enzymatic or Regulatory Activity; 4.2.2 Group II-Protein Therapeutics with Special Targeting Activity; 4.2.3 Group III-Proteinaceous Vaccines.
650 0 _aNanostructured materials.
650 0 _aNanomedicine.
650 0 _aNanobiotechnology.
650 7 _aTECHNOLOGY & ENGINEERING / Engineering (General)
_2bisacsh
650 7 _aTECHNOLOGY & ENGINEERING / Reference
_2bisacsh
650 7 _aNanobiotechnology.
_2fast
_0(OCoLC)fst01894713
650 7 _aNanomedicine.
_2fast
_0(OCoLC)fst01744350
650 7 _aNanostructured materials.
_2fast
_0(OCoLC)fst01032630
655 4 _aElectronic books.
700 1 _aGrumezescu, Alexandru Mihai,
_eeditor.
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780323428668
999 _c503921
_d503856