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001 978-3-030-54061-6
003 DE-He213
005 20211012164900.0
007 cr nn 008mamaa
008 200731s2020 sz | s |||| 0|eng d
020 _a9783030540616
_9978-3-030-54061-6
024 7 _a10.1007/978-3-030-54061-6
_2doi
050 4 _aTP248.13-248.65
072 7 _aTCB
_2bicssc
072 7 _aSCI010000
_2bisacsh
072 7 _aTCB
_2thema
082 0 4 _a660.6
_223
245 1 0 _aAptamers in Biotechnology
_h[electronic resource] /
_cedited by Katharina Urmann, Johanna-Gabriela Walter.
250 _a1st ed. 2020.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2020.
300 _aVII, 215 p. 61 illus., 47 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Biochemical Engineering/Biotechnology,
_x1616-8542 ;
_v174
505 0 _aBiophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics.
520 _aThis book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology. .
650 0 _aBiotechnology.
650 0 _aImmunology.
650 0 _aNucleic acids.
650 0 _aNanochemistry.
650 0 _aChromatography.
650 0 _aBiomedical engineering.
650 1 4 _aBiotechnology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C12002
650 2 4 _aImmunology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B14000
650 2 4 _aNucleic Acid Chemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/L14011
650 2 4 _aNanochemistry.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C33000
650 2 4 _aChromatography.
_0https://scigraph.springernature.com/ontologies/product-market-codes/C11030
650 2 4 _aBiomedical Engineering and Bioengineering.
_0https://scigraph.springernature.com/ontologies/product-market-codes/T2700X
700 1 _aUrmann, Katharina.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWalter, Johanna-Gabriela.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030540609
776 0 8 _iPrinted edition:
_z9783030540623
776 0 8 _iPrinted edition:
_z9783030540630
830 0 _aAdvances in Biochemical Engineering/Biotechnology,
_x1616-8542 ;
_v174
856 4 0 _uhttps://doi.org/10.1007/978-3-030-54061-6
912 _aZDB-2-CMS
912 _aZDB-2-SXC
950 _aChemistry and Materials Science (SpringerNature-11644)
950 _aChemistry and Material Science (R0) (SpringerNature-43709)
999 _c547910
_d547845