Bioresorbable polymers for biomedical applications : from fundamentals to translational medicine / edited by Giuseppe Perale and J�ons Hilborn.

Front Cover; Bioresorbable Polymers for Biomedical Applications; Related titles; Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine; Copyright; Dedication; Contents; List of contributors; Woodhead Publishing Series in Biomaterials; Foreword; 1 A quick glance at history; 2 Joining forces; 3 Some facts and figures; 4 Imaging the future; 5 So what about bioresorbable polymers?; One -- Fundamentals and considerations of bioresorbable polymers for biomedical applications; 1 -- Introduction to bioresorbable polymers for biomedical applications

1.1 General concepts1.2 History of biopolymers technology; 1.2.1 Degradability, toxicity, and biocompatibility; 1.2.2 Compounding, mechanical properties, and degradation time; 1.2.3 Extrusion and fiber manufacturing; 1.2.4 Molding; 1.2.5 Coating, solvent casting, and foaming; 1.2.6 Hydrogels manufacturing; 1.2.7 Micro- and nanoparticles manufacturing; 1.2.8 Additive manufacturing; 1.2.9 Composite materials; 1.2.10 Sterilization; 1.3 State of art; 1.3.1 Aliphatic polyesters; 1.3.2 Natural biopolymers; 1.3.3 Poly(ester-ether); 1.3.4 Poly(ortho esters); 1.3.5 Polyphosphazenes

1.3.6 Polyanhydrides1.3.7 Poly(amino acids); 1.3.8 Polyalkylcyanoacrylates; 1.3.9 Poly(propylene fumarate); 1.3.10 Poly(vinyl alcohol); 1.4 Future trends; References; 2 -- Natural polymers: a source of inspiration; 2.1 Introduction; 2.2 Typical production processes for biomaterial synthesis; 2.2.1 Self-assembly; 2.2.2 Template-driven reproduction; 2.3 Exceptional material properties found in nature; 2.3.1 Superhydrophobicity; 2.3.2 Adhesion; 2.3.3 Self-healing; 2.4 Natural biomaterials and mimics thereof used for tissue engineering; 2.4.1 Decellularized extracellular matrix; 2.4.2 Collagen

2.4.3 Elastin and elastin-like macromolecules2.4.4 Silk; 2.4.5 Scaffolds from marine origin; 2.5 Bioadhesives and medical glues; 2.5.1 Bioadhesives in the wet and dry environment; 2.5.2 Strong adhesive systems; 2.5.3 Weak adhesive systems; 2.6 Polymers used in drug delivery/release systems; 2.6.1 Natural drug carriers versus smart drug release systems; 2.6.2 Drug delivery on request; 2.7 Conclusions; References; 3 -- Bioresorbability of polymers: chemistry, mechanisms, and modeling; 3.1 Introduction; 3.2 Degradation pathway and factors affecting degradation rate

3.3 Modeling degradation of bioresorbable polymers3.3.1 Empirical models; 3.3.2 Semiempirical models; 3.3.3 Mechanistic models; 3.3.3.1 Deterministic models; 3.3.3.2 Stochastic models; References; 4 -- The innate immune response: a key factor in biocompatibility; 4.1 Immune system; 4.2 Innate immunity; 4.3 Complement system; 4.4 The contact/kallikrein and coagulation systems; 4.5 Thromboinflammation; 4.6 Innate immunity activation on artificial material surfaces; 4.7 Foreign body reactions on biomaterials; 4.8 Degradation of commonly used resorbable polymers

Includes index.