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20190719103415.0 |
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| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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161229s2017 enk ob 001 0 eng d |
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| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780128095027 |
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(electronic bk.) |
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0128095024 |
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(electronic bk.) |
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9780128094112 |
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0128094117 |
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(OCoLC)967258286 |
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R858 |
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2017 C-603 |
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WB 102 |
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610.285 |
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23 |
| 245 00 - TITLE STATEMENT |
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| Title |
Progress and challenges in precision medicine / |
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edited by Mukesh Verma, Debmalya Barh. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
London, United Kingdom : |
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Academic Press, |
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2017. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource |
| 505 0# - |
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| Formatted contents note |
Front Cover; Progress and Challengesin Precision Medicine; Progress and Challenges in Precision Medicine; Copyright; Contents; List of Contributors; Biography; MUKESH VERMA; DEBMALYA BARH; Dedication; Preface; 1 -- Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment; 1. WHAT IS PRECISION MEDICINE? PERSONALIZED MEDICINE VERSUS PRECISION MEDICINE (C. HIZEL, P. HAMET, AND J. TREMBLAY); 1.1 Precision Medicine in Complex Chronic Disease: A Focus on Diabetes; 2. PRECISION MEDICINE FOR POPULATION HEALTH (G. BARTLETT); 3. CONCLUSION |
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5.4 Noninvasive Prenatal Testing5.5 Disease Gene Identification; 6. REGULATORY CONCERNS WITH NGS CLINICAL GENOMICS; 7. CONCLUSION; REFERENCES; 3 -- Phenotyping in Precision Medicine; 1. INTRODUCTION; 2. DEEP PHENOTYPING; 3. EXPRESSIVITY AND PENETRANCE; 4. EXPRESSIVITY; 5. PENETRANCE; 6. PHENOTYPIC VARIATION IN EXPRESSIVITY AND PENETRANCE; 7. PLEIOTROPY; 8. DISEASES AND PHENOTYPES; 9. CANCER; 10. DIABETES; 11. RESPIRATORY DISORDERS; 12. ENCEPHALOPATHY; 13. DATA MINING AND PHENOTYPING; 14. APPROACHES FOR PHENOTYPING; 15. FUTURE DIRECTIONS; REFERENCES |
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4 -- Cancer Genetic Screening and Ethical Considerations for Precision Medicine1. INTRODUCTION; 2. GENETIC TESTING IN HEREDITARY CANCERS; 2.1 Genetic Testing for Hereditary Breast and Ovarian Cancers; 2.2 Genetic Testing for Hereditary Colorectal Cancers; 2.3 Genetic Testing for Lung Cancers; 3. ETHICAL ISSUES RELATED TO CANCER GENETIC SCREENING; 3.1 Competency of Genetic Screening Laboratories and Medical Personnel; 3.2 Direct-To-Consumers Genetic Testing; 3.3 Individual Rights Versus Community Rights; 3.4 Individual Informed Consent; 3.5 Return of the Results for Pediatric Patients |
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3.6 Environmental and Distributive Justice3.7 Cancer Screening and Discrimination; 3.8 Cancer Screening and Stigma; 3.9 Implications of Genetic-Based Cancer Screening at the Population Level; 4. SUMMARY AND CONCLUSIONS; REFERENCES; 5 -- Precision Medicine in Primary Health Care; 1. THE CASE FOR PRIMARY HEALTH CARE; 2. PRECISION MEDICINE IN PRIMARY HEALTH CARE: WARFARIN AND PHARMACOGENOMICS; 3. PRECISION MEDICINE IN PRIMARY HEALTH CARE: CREATING AN INFORMATICS SYSTEM; 4. PRECISION MEDICINE: A FEASIBILITY STUDY FOR PRIMARY HEALTH CARE; 4.1 Outcomes; 4.2 Statistical Analysis; 4.3 Ethics |
| 650 #0 - |
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| Topical term or geographic name as entry element |
Medical innovations. |
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Medical informatics. |
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HEALTH & FITNESS |
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HEALTH & FITNESS |
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MEDICAL |
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MEDICAL |
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MEDICAL |
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MEDICAL |
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MEDICAL |
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MEDICAL |
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Medical informatics. |
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Medical innovations. |
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Precision Medicine. |
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Medical Informatics. |
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| Personal name |
Verma, Mukesh, |
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editor. |
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| Personal name |
Barh, Debmalya, |
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editor. |
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| Uniform Resource Identifier |
http://www.sciencedirect.com/science/book/9780128094112 |
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text |
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txt |
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rdacontent |
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computer |
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online resource |
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rdacarrier |
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Includes bibliographical references and index. |
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Online resource, title from PDF title page (EBSCO, viewed January 25, 2017). |
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Reference. |
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Alternative Medicine. |
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Family & General Practice. |
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Holistic Medicine. |
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Osteopathy. |
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fast |
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(OCoLC)fst01014175 |
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fast |
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(OCoLC)fst01014181 |
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(DNLM)D057285 |
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(DNLM)D008490 |
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Fulltext. |
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Internet Resources. |
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ScienceDirect |
