Wellcome

Progress and challenges in precision medicine / edited by Mukesh Verma, Debmalya Barh.

Contributor(s): Verma, Mukesh [editor.] | Barh, Debmalya [editor.]Material type: TextTextPublication details: London, United Kingdom : Academic Press, 2017Description: 1 online resourceContent type: text Media type: computer Carrier type: online resourceISBN: 9780128095027; 0128095024Subject(s): Medical innovations | Medical informatics | HEALTH & FITNESS -- Holism | HEALTH & FITNESS -- Reference | MEDICAL -- Alternative Medicine | MEDICAL -- Atlases | MEDICAL -- Essays | MEDICAL -- Family & General Practice | MEDICAL -- Holistic Medicine | MEDICAL -- Osteopathy | Medical informatics | Medical innovations | Precision Medicine | Medical InformaticsGenre/Form: Fulltext. | Internet Resources.DDC classification: 610.285 LOC classification: R858NLM classification: 2017 C-603 | WB 102Online resources: ScienceDirect
Contents:
Front Cover; Progress and Challengesin Precision Medicine; Progress and Challenges in Precision Medicine; Copyright; Contents; List of Contributors; Biography; MUKESH VERMA; DEBMALYA BARH; Dedication; Preface; 1 -- Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment; 1. WHAT IS PRECISION MEDICINE? PERSONALIZED MEDICINE VERSUS PRECISION MEDICINE (C. HIZEL, P. HAMET, AND J. TREMBLAY); 1.1 Precision Medicine in Complex Chronic Disease: A Focus on Diabetes; 2. PRECISION MEDICINE FOR POPULATION HEALTH (G. BARTLETT); 3. CONCLUSION
5.4 Noninvasive Prenatal Testing5.5 Disease Gene Identification; 6. REGULATORY CONCERNS WITH NGS CLINICAL GENOMICS; 7. CONCLUSION; REFERENCES; 3 -- Phenotyping in Precision Medicine; 1. INTRODUCTION; 2. DEEP PHENOTYPING; 3. EXPRESSIVITY AND PENETRANCE; 4. EXPRESSIVITY; 5. PENETRANCE; 6. PHENOTYPIC VARIATION IN EXPRESSIVITY AND PENETRANCE; 7. PLEIOTROPY; 8. DISEASES AND PHENOTYPES; 9. CANCER; 10. DIABETES; 11. RESPIRATORY DISORDERS; 12. ENCEPHALOPATHY; 13. DATA MINING AND PHENOTYPING; 14. APPROACHES FOR PHENOTYPING; 15. FUTURE DIRECTIONS; REFERENCES
4 -- Cancer Genetic Screening and Ethical Considerations for Precision Medicine1. INTRODUCTION; 2. GENETIC TESTING IN HEREDITARY CANCERS; 2.1 Genetic Testing for Hereditary Breast and Ovarian Cancers; 2.2 Genetic Testing for Hereditary Colorectal Cancers; 2.3 Genetic Testing for Lung Cancers; 3. ETHICAL ISSUES RELATED TO CANCER GENETIC SCREENING; 3.1 Competency of Genetic Screening Laboratories and Medical Personnel; 3.2 Direct-To-Consumers Genetic Testing; 3.3 Individual Rights Versus Community Rights; 3.4 Individual Informed Consent; 3.5 Return of the Results for Pediatric Patients
3.6 Environmental and Distributive Justice3.7 Cancer Screening and Discrimination; 3.8 Cancer Screening and Stigma; 3.9 Implications of Genetic-Based Cancer Screening at the Population Level; 4. SUMMARY AND CONCLUSIONS; REFERENCES; 5 -- Precision Medicine in Primary Health Care; 1. THE CASE FOR PRIMARY HEALTH CARE; 2. PRECISION MEDICINE IN PRIMARY HEALTH CARE: WARFARIN AND PHARMACOGENOMICS; 3. PRECISION MEDICINE IN PRIMARY HEALTH CARE: CREATING AN INFORMATICS SYSTEM; 4. PRECISION MEDICINE: A FEASIBILITY STUDY FOR PRIMARY HEALTH CARE; 4.1 Outcomes; 4.2 Statistical Analysis; 4.3 Ethics
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Holdings
Item type Current library Call number Status Date due Barcode
Ebooks Ebooks Mysore University Main Library
Not for loan EBKELV664

Includes bibliographical references and index.

Online resource, title from PDF title page (EBSCO, viewed January 25, 2017).

Front Cover; Progress and Challengesin Precision Medicine; Progress and Challenges in Precision Medicine; Copyright; Contents; List of Contributors; Biography; MUKESH VERMA; DEBMALYA BARH; Dedication; Preface; 1 -- Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment; 1. WHAT IS PRECISION MEDICINE? PERSONALIZED MEDICINE VERSUS PRECISION MEDICINE (C. HIZEL, P. HAMET, AND J. TREMBLAY); 1.1 Precision Medicine in Complex Chronic Disease: A Focus on Diabetes; 2. PRECISION MEDICINE FOR POPULATION HEALTH (G. BARTLETT); 3. CONCLUSION

5.4 Noninvasive Prenatal Testing5.5 Disease Gene Identification; 6. REGULATORY CONCERNS WITH NGS CLINICAL GENOMICS; 7. CONCLUSION; REFERENCES; 3 -- Phenotyping in Precision Medicine; 1. INTRODUCTION; 2. DEEP PHENOTYPING; 3. EXPRESSIVITY AND PENETRANCE; 4. EXPRESSIVITY; 5. PENETRANCE; 6. PHENOTYPIC VARIATION IN EXPRESSIVITY AND PENETRANCE; 7. PLEIOTROPY; 8. DISEASES AND PHENOTYPES; 9. CANCER; 10. DIABETES; 11. RESPIRATORY DISORDERS; 12. ENCEPHALOPATHY; 13. DATA MINING AND PHENOTYPING; 14. APPROACHES FOR PHENOTYPING; 15. FUTURE DIRECTIONS; REFERENCES

4 -- Cancer Genetic Screening and Ethical Considerations for Precision Medicine1. INTRODUCTION; 2. GENETIC TESTING IN HEREDITARY CANCERS; 2.1 Genetic Testing for Hereditary Breast and Ovarian Cancers; 2.2 Genetic Testing for Hereditary Colorectal Cancers; 2.3 Genetic Testing for Lung Cancers; 3. ETHICAL ISSUES RELATED TO CANCER GENETIC SCREENING; 3.1 Competency of Genetic Screening Laboratories and Medical Personnel; 3.2 Direct-To-Consumers Genetic Testing; 3.3 Individual Rights Versus Community Rights; 3.4 Individual Informed Consent; 3.5 Return of the Results for Pediatric Patients

3.6 Environmental and Distributive Justice3.7 Cancer Screening and Discrimination; 3.8 Cancer Screening and Stigma; 3.9 Implications of Genetic-Based Cancer Screening at the Population Level; 4. SUMMARY AND CONCLUSIONS; REFERENCES; 5 -- Precision Medicine in Primary Health Care; 1. THE CASE FOR PRIMARY HEALTH CARE; 2. PRECISION MEDICINE IN PRIMARY HEALTH CARE: WARFARIN AND PHARMACOGENOMICS; 3. PRECISION MEDICINE IN PRIMARY HEALTH CARE: CREATING AN INFORMATICS SYSTEM; 4. PRECISION MEDICINE: A FEASIBILITY STUDY FOR PRIMARY HEALTH CARE; 4.1 Outcomes; 4.2 Statistical Analysis; 4.3 Ethics

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